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Isoforms of renal Na-K-2Cl cotransporter NKCC2: expression and functional significance

The renal Na-K-2Cl cotransporter (NKCC2, BSC1) is selectively expressed in the apical membrane of cells of the thick ascending limb of the loop of Henle (TAL) and macula densa. NKCC2-dependent salt transport constitutes the major apical entry pathway for transepithelial salt reabsorption in the TAL....

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Autori principali: Castrop, Hayo, Schnermann, Jurgen
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576146/
https://ncbi.nlm.nih.gov/pubmed/18495801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00106.2008
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