Osmoregulation Requires Brain Expression of the Renal Na-K-2Cl Cotransporter NKCC2

The Na-K-2Cl cotransporter 2 (NKCC2) was thought to be kidney specific. Here we show expression in the brain hypothalamo-neurohypophyseal system (HNS), wherein upregulation follows osmotic stress. The HNS controls osmotic stability through the synthesis and release of the neuropeptide hormone, argin...

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Publicado no:J Neurosci
Main Authors: Konopacka, Agnieszka, Qiu, Jing, Yao, Song T., Greenwood, Michael P., Greenwood, Mingkwan, Lancaster, Thomas, Inoue, Wataru, de Souza Mecawi, Andre, Vechiato, Fernanda M.V., de Lima, Juliana B.M., Coletti, Ricardo, Hoe, See Ziau, Martin, Andrew, Lee, Justina, Joseph, Marina, Hindmarch, Charles, Paton, Julian, Antunes-Rodrigues, Jose, Bains, Jaideep, Murphy, David
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380993/
https://ncbi.nlm.nih.gov/pubmed/25834041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4121-14.2015
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