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Regulation of Akt signaling by O-GlcNAc in euglycemia

The hexosamine biosynthesis pathway (HBP) regulates the posttranslational modification of nuclear and cytoplasmic protein by O-linked N-acetylglucosamine (O-GlcNAc). Numerous studies have demonstrated that, in hyperglycemic conditions, excessive glucose flux through this pathway contributes to the d...

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Autori principali: Soesanto, Yudi A., Luo, Bai, Jones, Deborah, Taylor, Rodrick, Gabrielsen, J. Scott, Parker, Glendon, McClain, Donald A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575895/
https://ncbi.nlm.nih.gov/pubmed/18728220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.90366.2008
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