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Down-regulation of Sprouty2 via p38 MAPK plays a key role in the induction of cellular apoptosis by tumor necrosis factor-α

Mammalian Sprouty2 (Spry2) is a key regulator of the receptor tyrosine kinase/ERK signaling pathway and involved in many biological processes, including cell growth, migration and tumor suppression. Here, we demonstrated that the intracellular protein level of Spry2 was significantly down-regulated...

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Sonraí Bibleagrafaíochta
Main Authors: Ding, Wei, Warburton, David
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575769/
https://ncbi.nlm.nih.gov/pubmed/18713620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.08.037
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