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Down-regulation of Sprouty2 via p38 MAPK plays a key role in the induction of cellular apoptosis by tumor necrosis factor-α
Mammalian Sprouty2 (Spry2) is a key regulator of the receptor tyrosine kinase/ERK signaling pathway and involved in many biological processes, including cell growth, migration and tumor suppression. Here, we demonstrated that the intracellular protein level of Spry2 was significantly down-regulated...
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Main Authors: | , |
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Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
2008
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575769/ https://ncbi.nlm.nih.gov/pubmed/18713620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.08.037 |
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