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Signal integration: a framework for understanding the efficacy of therapeutics targeting the human EGFR family

The human EGFR (HER) family is essential for communication between many epithelial cancer cell types and the tumor microenvironment. Therapeutics targeting the HER family have demonstrated clinical success in the treatment of diverse epithelial cancers. Here we propose that the success of HER family...

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Detalhes bibliográficos
Main Authors: Shepard, H. Michael, Brdlik, Cathleen M., Schreiber, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575712/
https://ncbi.nlm.nih.gov/pubmed/18982164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36049
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