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Progress in understanding ferroptosis and challenges in its targeting for therapeutic benefit

Ferroptosis is an iron-dependent cell death modality driven by oxidative phospholipid damage. In contrast to apoptosis, which enables organisms to eliminate targeted cells purposefully at specific times, ferroptosis appears to be a vulnerability of cells that otherwise use high levels of polyunsatur...

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Detalhes bibliográficos
Publicado no:Cell Chem Biol
Main Authors: Zou, Yilong, Schreiber, Stuart L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7346472/
https://ncbi.nlm.nih.gov/pubmed/32302583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2020.03.015
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