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How the thymus designs antigen-specific and self-tolerant T cell receptor sequences
T lymphocytes (T cells) orchestrate adaptive immune responses that clear pathogens from infected hosts. T cells recognize short peptides (p) derived from antigenic proteins bound to protein products of the MHC genes. Recognition occurs when T cell receptor (TCR) proteins expressed on T cells bind su...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575478/ https://ncbi.nlm.nih.gov/pubmed/18946038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808081105 |
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