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Evolutionary redefinition of immunoglobulin light chain isotypes in tetrapods using molecular markers

The phylogenetic relationships of Ig light chain (IGL) genes are difficult to resolve, because these genes are short and evolve relatively fast. Here, we classify the IGL sequences from 12 tetrapod species into three distinct groups (κ, λ, and σ isotypes) using conserved amino acid residues, recombi...

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Autores principales: Das, Sabyasachi, Nikolaidis, Nikolas, Klein, Jan, Nei, Masatoshi
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575474/
https://ncbi.nlm.nih.gov/pubmed/18940927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808800105
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