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Evolutionary dynamics of the immunoglobulin heavy chain variable region genes in vertebrates

Immunoglobulin heavy chains are polypeptides encoded by four genes: variable (IGHV), joining (IGHJ), diversity (IGHD), and constant (IGHC) region genes. The number of IGHV genes varies from species to species. To understand the evolution of the IGHV multigene family, we identified and analyzed the I...

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Bibliografische gegevens
Hoofdauteurs: Das, Sabyasachi, Nozawa, Masafumi, Klein, Jan, Nei, Masatoshi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386433/
https://ncbi.nlm.nih.gov/pubmed/18196235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-007-0270-2
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