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Evolutionary dynamics of the immunoglobulin heavy chain variable region genes in vertebrates

Immunoglobulin heavy chains are polypeptides encoded by four genes: variable (IGHV), joining (IGHJ), diversity (IGHD), and constant (IGHC) region genes. The number of IGHV genes varies from species to species. To understand the evolution of the IGHV multigene family, we identified and analyzed the I...

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Main Authors: Das, Sabyasachi, Nozawa, Masafumi, Klein, Jan, Nei, Masatoshi
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386433/
https://ncbi.nlm.nih.gov/pubmed/18196235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-007-0270-2
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