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Evolutionary dynamics of the immunoglobulin heavy chain variable region genes in vertebrates
Immunoglobulin heavy chains are polypeptides encoded by four genes: variable (IGHV), joining (IGHJ), diversity (IGHD), and constant (IGHC) region genes. The number of IGHV genes varies from species to species. To understand the evolution of the IGHV multigene family, we identified and analyzed the I...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2386433/ https://ncbi.nlm.nih.gov/pubmed/18196235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-007-0270-2 |
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