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Evolutionary redefinition of immunoglobulin light chain isotypes in tetrapods using molecular markers

The phylogenetic relationships of Ig light chain (IGL) genes are difficult to resolve, because these genes are short and evolve relatively fast. Here, we classify the IGL sequences from 12 tetrapod species into three distinct groups (κ, λ, and σ isotypes) using conserved amino acid residues, recombi...

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Bibliografiske detaljer
Main Authors: Das, Sabyasachi, Nikolaidis, Nikolas, Klein, Jan, Nei, Masatoshi
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575474/
https://ncbi.nlm.nih.gov/pubmed/18940927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808800105
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