Deficiency in ubiquitin ligase TRIM2 causes accumulation of neurofilament light chain and neurodegeneration

TRIM RING finger proteins have been shown to play an important role in cancerogenesis, in the pathogenesis of some human hereditary disorders, and in the defense against viral infection, but the function of the majority of TRIM proteins remains unknown. Here, we show that TRIM RING finger protein TR...

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Bibliografiske detaljer
Main Authors: Balastik, Martin, Ferraguti, Francesco, Pires-da Silva, André, Lee, Tae Ho, Alvarez-Bolado, Gonzalo, Lu, Kun Ping, Gruss, Peter
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575299/
https://ncbi.nlm.nih.gov/pubmed/18687884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802261105
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