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Deficiency in ubiquitin ligase TRIM2 causes accumulation of neurofilament light chain and neurodegeneration

TRIM RING finger proteins have been shown to play an important role in cancerogenesis, in the pathogenesis of some human hereditary disorders, and in the defense against viral infection, but the function of the majority of TRIM proteins remains unknown. Here, we show that TRIM RING finger protein TR...

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Detalhes bibliográficos
Main Authors: Balastik, Martin, Ferraguti, Francesco, Pires-da Silva, André, Lee, Tae Ho, Alvarez-Bolado, Gonzalo, Lu, Kun Ping, Gruss, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575299/
https://ncbi.nlm.nih.gov/pubmed/18687884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802261105
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