Minimization of exogenous signals in ES cell culture induces rostral hypothalamic differentiation

Embryonic stem (ES) cells differentiate into neuroectodermal progenitors when cultured as floating aggregates in serum-free conditions. Here, we show that strict removal of exogenous patterning factors during early differentiation steps induces efficient generation of rostral hypothalamic-like proge...

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Detalhes bibliográficos
Main Authors: Wataya, Takafumi, Ando, Satoshi, Muguruma, Keiko, Ikeda, Hanako, Watanabe, Kiichi, Eiraku, Mototsugu, Kawada, Masako, Takahashi, Jun, Hashimoto, Nobuo, Sasai, Yoshiki
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575295/
https://ncbi.nlm.nih.gov/pubmed/18697938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803078105
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