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Structures of invisible, excited protein states by relaxation dispersion NMR spectroscopy

Molecular function is often predicated on excursions between ground states and higher energy conformers that can play important roles in ligand binding, molecular recognition, enzyme catalysis, and protein folding. The tools of structural biology enable a detailed characterization of ground state st...

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Bibliographic Details
Main Authors: Vallurupalli, Pramodh, Hansen, D. Flemming, Kay, Lewis E.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575287/
https://ncbi.nlm.nih.gov/pubmed/18701719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804221105
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