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Total Synthesis, Structure Revision, and Absolute Configuration of (−)-Brevenal

Total synthesis of structure 1 originally proposed for brevenal, a nontoxic polycyclic ether natural product isolated from the Florida red tide dinoflagellate, Karenia brevis, was accomplished. The key features of the synthesis involved (i) convergent assembly of the pentacyclic polyether skeleton b...

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Bibliographic Details
Main Authors: Fuwa, Haruhiko, Ebine, Makoto, Bourdelais, Andrea J., Baden, Daniel G., Sasaki, Makoto
Format: Artigo
Language:Inglês
Published: 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575246/
https://ncbi.nlm.nih.gov/pubmed/17177450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja066772y
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