Angiopoietin-2 is associated with decreased endothelial nitric oxide and poor clinical outcome in severe falciparum malaria

Adherence of parasitized erythrocytes to activated endothelium causes microvascular obstruction, tissue ischemia, and clinical complications in severe malaria (SM); however, the mechanisms leading to endothelial activation remain unclear. The angiogenic factors, angiopoietin-2 (Ang-2) and vascular e...

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Détails bibliographiques
Auteurs principaux: Yeo, Tsin W., Lampah, Daniel A., Gitawati, Retno, Tjitra, Emiliana, Kenangalem, Enny, Piera, Kim, Price, Ric N., Duffull, Stephen B., Celermajer, David S., Anstey, Nicholas M.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2008
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575222/
https://ncbi.nlm.nih.gov/pubmed/18957536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805782105
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