Assembly and Misassembly of Cystic Fibrosis Transmembrane Conductance Regulator: Folding Defects Caused by Deletion of F508 Occur Before and After the Calnexin-dependent Association of Membrane Spanning Domain (MSD) 1 and MSD2

Lignende værker

• Mechanisms for Rescue of Correctable Folding Defects in CFTRΔF508
  af: Grove, Diane E., et al.
  Udgivet: (2009)
• VX-809 corrects folding defects in cystic fibrosis transmembrane conductance regulator protein through action on membrane-spanning domain 1
  af: Ren, Hong Yu, et al.
  Udgivet: (2013)
• Deletion of Phenylalanine 508 in the Cystic Fibrosis Transmembrane Conductance Regulator Reduces Dimerization(♦): Deletion of Phenylalanine 508 in the First Nucleotide-binding Domain of the Cystic Fibrosis Transmembrane Conductance Regulator Increases Conformational Exchange and Inhibits Dimerization
  Udgivet: (2015)
• Most F508del-CFTR Is Targeted to Degradation at an Early Folding Checkpoint and Independently of Calnexin
  af: Farinha, Carlos M., et al.
  Udgivet: (2005)
• Pancreatic function and gene deletion F508 in cystic fibrosis.
  af: Borgo, G, et al.
  Udgivet: (1990)