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Inhibition of Growth Hormone Signaling by the Fasting-Induced Hormone FGF21
Starvation blocks the actions of growth hormone (GH) and inhibits growth through mechanisms that are not well understood. In this report, we demonstrate that fibroblast growth factor 21 (FGF21), a hormone induced by fasting, causes GH resistance. In liver, FGF21 reduces concentrations of the active...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575072/ https://ncbi.nlm.nih.gov/pubmed/18585098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2008.05.006 |
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