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Selective Disruption of Early/Recycling Endosomes: Release of Disulfide-Linked Cargo Mediated by a N-Alkyl-3β-Cholesterylamine-Capped Peptide

The use of endocytic uptake pathways to deliver poorly permeable molecules into mammalian cells is often plagued by entrapment and degradation of material in late endosomes and lysosomes. As a strategy to prevent the exposure of cargo to these highly hydrolytic membrane-sealed compartments, we synth...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Sun, Qi, Cai, Sutang, Peterson, Blake R.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575022/
https://ncbi.nlm.nih.gov/pubmed/18613675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja803380a
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