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Post-transcriptional gene regulation by HuR promotes a more tumorigenic phenotype
In a breast tumor xenograft model, the MCT-1 oncogene increases the in vivo tumorgenicity of MCF7 cells by promoting angiogenesis and inhibiting apoptosis. Increases in the tumor microvascular density are accompanied by a strong reduction in the levels of the angiogenesis inhibitor thrombospondin-1...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575016/ https://ncbi.nlm.nih.gov/pubmed/18641687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.215 |
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