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Antiapoptotic function of RNA-binding protein HuR effected through prothymosin α
We report the antiapoptotic effect of RNA-binding protein HuR, a critical regulator of the post-transcriptional fate of target transcripts. Among the most prominent mRNAs complexing with HuR is that encoding prothymosin α (ProTα), an inhibitor of the apoptosome. In HeLa cells, treatment with the apo...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1142594/ https://ncbi.nlm.nih.gov/pubmed/15861128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600661 |
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