Gonococcal lipooligosaccharide sialylation prevents complement-dependent killing by immune sera.

Previous investigators have demonstrated that a sialic acid residue is added to the terminal galactose moiety of gonococcal lipooligosaccharide (LOS) when incubated with 5'-CMP-N-acetylneuraminic acid. When this in vitro sialylation occurs, gonococci become resistant to the bactericidal activit...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Wetzler, L M, Barry, K, Blake, M S, Gotschlich, E C
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257500/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1729195/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.1.39-43.1992
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