Gonococcal lipooligosaccharide sialylation prevents complement-dependent killing by immune sera.

Previous investigators have demonstrated that a sialic acid residue is added to the terminal galactose moiety of gonococcal lipooligosaccharide (LOS) when incubated with 5'-CMP-N-acetylneuraminic acid. When this in vitro sialylation occurs, gonococci become resistant to the bactericidal activity of...

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Bibliografiske detaljer

Udgivet i:	Infect Immun
Principais autores:	Wetzler, L M, Barry, K, Blake, M S, Gotschlich, E C
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1992
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257500/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1729195/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.1.39-43.1992
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