Gonococcal lipooligosaccharide sialylation prevents complement-dependent killing by immune sera.

Previous investigators have demonstrated that a sialic acid residue is added to the terminal galactose moiety of gonococcal lipooligosaccharide (LOS) when incubated with 5'-CMP-N-acetylneuraminic acid. When this in vitro sialylation occurs, gonococci become resistant to the bactericidal activit...

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Dettagli Bibliografici
Autori principali: Wetzler, L M, Barry, K, Blake, M S, Gotschlich, E C
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1992
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC257500/
https://ncbi.nlm.nih.gov/pubmed/1729195
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