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Pd-Catalyzed Enantioselective Aerobic Oxidation of Secondary Alcohols: Applications to the Total Synthesis of Alkaloids

Enantioselective syntheses of the alkaloids (−)-aurantioclavine, (+)-amurensinine, (−)-lobeline, and (−)- and (+)-sedamine are described. The syntheses demonstrate the effectiveness of the Pd-catalyzed asymmetric oxidation of secondary alcohols in diverse contexts and the ability of this methodology...

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Detalhes bibliográficos
Main Authors: Krishnan, Shyam, Bagdanoff, Jeffrey T., Ebner, David C., Ramtohul, Yeeman K., Tambar, Uttam K., Stoltz, Brian M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574996/
https://ncbi.nlm.nih.gov/pubmed/18798630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja804738b
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