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DNA mismatch repair: Molecular mechanism, cancer, and ageing

DNA mismatch repair (MMR) proteins are ubiquitous players in a diverse array of important cellular functions. In its role in post-replication repair, MMR safeguards the genome correcting base mispairs arising as a result of replication errors. Loss of MMR results in greatly increased rates of sponta...

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Detalles Bibliográficos
Main Authors: Hsieh, Peggy, Yamane, Kazuhiko
Formato: Artigo
Idioma:Inglês
Publicado: 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574955/
https://ncbi.nlm.nih.gov/pubmed/18406444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2008.02.012
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