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DNA Mismatch Repair: Dr. Jekyll and Mr. Hyde?
In this issue, Peña-Diaz et al. (2012) describe a pathway for somatic mutation in nonlymphoid cells termed noncanonical DNA mismatch repair, whereby the error-prone translesion polymerase Pol-η substitutes for high-fidelity replicative polymerases to resynthesize excised regions opposite DNA damage....
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3457060/ https://ncbi.nlm.nih.gov/pubmed/22980456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.08.020 |
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