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Dissociation Between Superoxide Accumulation And Nitroglycerin- Induced Tolerance
We hypothesize that superoxide (O(2)(•−)) accumulation is not a crucial causative factor in inducing nitroglycerin (NTG) tolerance. In LLC-PK1 cells, pre-exposure to NTG resulted in increased O(2)(•−) accumulation and reduced cyclic guanosine monophophate (cGMP) response to NTG vs. vehicle control....
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2574757/ https://ncbi.nlm.nih.gov/pubmed/18653825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.138784 |
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