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Effects of obesity on the pharmacodynamics of nitroglycerin in conscious rats

Literature reports have suggested that hemodynamic response toward organic nitrates may be reduced in obese patients, but this effect has not been studied. We compared the mean arterial pressure (MAP) responses toward single doses of nitroglycerin (NTG), 0.5–50μg) in conscious Zucker obese (ZOB), Zu...

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Detalhes bibliográficos
Main Authors: Wang, Ellen Q., Fung, Ho-Leung
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751317/
https://ncbi.nlm.nih.gov/pubmed/12646000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/ps040428
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