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Morphine tolerance in the mouse ileum and colon

Repeated administration of morphine is associated with tolerance to its antinocicpetive properties. Constipation, however, remains the major side-effect of chronic exposure to morphine. In contrast, previous studies suggest that tolerance to opioids develops in the ileum from several species. In thi...

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Detalhes bibliográficos
Main Authors: Ross, Gracious R., Gabra, Bichoy H., Dewey, William L., Akbarali, Hamid I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574683/
https://ncbi.nlm.nih.gov/pubmed/18682567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.143438
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