Heat Shock Protein 90 Inhibitors Protect and Restore Pulmonary Endothelial Barrier Function

Heat shock protein 90 (hsp90) inhibitors inactivate and/or degrade various client proteins, including many involved in inflammation. Increased vascular permeability is a hallmark of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Thus, we tested the hypothesis that hsp90 inhi...

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Main Authors: Antonov, Alexander, Snead, Connie, Gorshkov, Boris, Antonova, Galina N., Verin, Alexander D., Catravas, John D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Thoracic Society 2008
Ábhair:
Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574526/
https://ncbi.nlm.nih.gov/pubmed/18474672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0324OC
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