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Differentiated thyroid cancer cell invasion is regulated through epidermal growth factor receptor-dependent activation of matrix metalloproteinase (MMP)-2/gelatinase A

Mechanisms of invasion in thyroid cancer remain poorly understood. We hypothesized that signaling via the epidermal growth factor receptor (EGFR) stimulates thyroid cancer cell invasion by altering the expression and cleavage of matrix metalloproteinases (MMPs). Papillary and follicular carcinoma ce...

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Detalhes bibliográficos
Main Authors: Yeh, Michael W, Rougier, Jean-Philippe, Park, Jin-Woo, Duh, Quan-Yang, Wong, Mariwil, Werb, Zena, Clark, Orlo H
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574514/
https://ncbi.nlm.nih.gov/pubmed/17158762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/erc.1.01226
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