Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas

Matrix metalloproteinases (MMPs) have been implicated as important factors in gliomas since they may both facilitate invasion into the surrounding brain and participate in neovascularization. We have tested the hypothesis that deregulated expression of gelatinase-A or B, or an activator of gelatinas...

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Main Authors: Forsyth, P A, Wong, H, Laing, T D, Rewcastle, N B, Morris, D G, Muzik, H, Leco, K J, Johnston, R N, Brasher, P M A, Sutherland, G, Edwards, D R
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1999
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362801/
https://ncbi.nlm.nih.gov/pubmed/10206300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6990291
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