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Structural Characteristics of the α-Synuclein Oligomers Stabilized by the Flavonoid Baicalein

The flavonoid baicalein inhibits fibrillation of α-synuclein, which is a major component of the Lewy bodies in Parkinson’s disease. It has been known that baicalein induces the formation of the α-synuclein oligomers and consequently prevents its fibrillation. In order to evaluate structural properti...

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Main Authors: Hong, Dong-Pyo, Fink, Anthony L., Uversky, Vladimir N.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573395/
https://ncbi.nlm.nih.gov/pubmed/18775438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.08.039
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