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Smoking and Parkinson’s disease: Does nicotine affect α-synuclein fibrillation?

α-Synuclein is a small presynaptic protein (14,460 D) that is abundantly distributed in the brain. Although, its function is unknown, the aggregated form of α-synuclein is a pathological hallmark of several neurodegenerative diseases, including Parkinson’s disease (PD). Epidemiological studies have...

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Detalhes bibliográficos
Main Authors: Hong, Dong-Pyo, Fink, Anthony L., Uversky, Vladimir N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647853/
https://ncbi.nlm.nih.gov/pubmed/19013262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2008.09.026
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