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Polycation-induced oligomerization and accelerated fibrillation of human α-synuclein in vitro

The aggregation and fibrillation of α-synuclein has been implicated as a causative factor in Parkinson’s disease and several other neurodegenerative disorders known as synucleinopathies. The effect of different factors on the process of fibril formation has been intensively studied in vitro. We show...

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Bibliographic Details
Main Authors: Goers, John, Uversky, Vladimir N., Fink, Anthony L.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323845/
https://ncbi.nlm.nih.gov/pubmed/12649428
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