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The Schizosaccharomyces pombe Pfh1p DNA Helicase Is Essential for the Maintenance of Nuclear and Mitochondrial DNA

Schizosaccharomyces pombe Pfh1p is an essential member of the Pif family of 5′-3′ DNA helicases. The two Saccharomyces cerevisiae homologs, Pif1p and Rrm3p, function in nuclear DNA replication, telomere length regulation, and mitochondrial genome integrity. We demonstrate here the existence of multi...

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Bibliographic Details
Main Authors: Pinter, Stefan F., Aubert, Sarah D., Zakian, Virginia A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573227/
https://ncbi.nlm.nih.gov/pubmed/18725402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00191-08
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