Hepatitis C Virus Infection Induces Apoptosis through a Bax-Triggered, Mitochondrion-Mediated, Caspase 3-Dependent Pathway

We previously reported that cells harboring the hepatitis C virus (HCV) RNA replicon as well as those expressing HCV NS3/4A exhibited increased sensitivity to suboptimal doses of apoptotic stimuli to undergo mitochondrion-mediated apoptosis (Y. Nomura-Takigawa, et al., J. Gen. Virol. 87:1935-1945, 2...

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Detalhes bibliográficos
Main Authors: Deng, Lin, Adachi, Tetsuya, Kitayama, Kikumi, Bungyoku, Yasuaki, Kitazawa, Sohei, Ishido, Satoshi, Shoji, Ikuo, Hotta, Hak
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573220/
https://ncbi.nlm.nih.gov/pubmed/18768989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00395-08
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