Hepatitis C Virus Infection Promotes Hepatic Gluconeogenesis through an NS5A-Mediated, FoxO1-Dependent Pathway

Chronic hepatitis C virus (HCV) infection is often associated with type 2 diabetes. However, the precise mechanism underlying this association is still unclear. Here, using Huh-7.5 cells either harboring HCV-1b RNA replicons or infected with HCV-2a, we showed that HCV transcriptionally upregulated t...

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Autores principales: Deng, Lin, Shoji, Ikuo, Ogawa, Wataru, Kaneda, Shusaku, Soga, Tomoyoshi, Jiang, Da-peng, Ide, Yoshi-Hiro, Hotta, Hak
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2011
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165828/
https://ncbi.nlm.nih.gov/pubmed/21697492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00146-11
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