Accelerated Prion Disease Pathogenesis in Toll-Like Receptor 4 Signaling-Mutant Mice

Prion diseases such as scrapie involve the accumulation of disease-specific prion protein, PrP(Sc), in the brain. Toll-like receptors (TLRs) are a family of proteins that recognize microbial constituents and are central players in host innate immune responses. The TLR9 agonist unmethylated CpG DNA w...

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Detaylı Bibliyografya
Asıl Yazarlar: Spinner, Daryl S., Cho, In Soo, Park, Seung Yong, Kim, Jae Il, Meeker, Harry C., Ye, Xuemin, LaFauci, Giuseppe, Kerr, Daniel J., Flory, Michael J., Kim, Bo Sook, Kascsak, Regina B., Wisniewski, Thomas, Levis, William R., Schuller-Levis, Georgia B., Carp, Richard I., Park, Eunkyue, Kascsak, Richard J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2008
Konular:
Pathogenesis and Immunity
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573175/
https://ncbi.nlm.nih.gov/pubmed/18715916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00522-08
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