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Engineered Intermonomeric Disulfide Bonds in the Globular Domain of Newcastle Disease Virus Hemagglutinin-Neuraminidase Protein: Implications for the Mechanism of Fusion Promotion

The promotion of membrane fusion by Newcastle disease virus (NDV) requires an interaction between the viral hemagglutinin-neuraminidase (HN) and fusion (F) proteins, although the mechanism by which this interaction regulates fusion is not clear. The NDV HN protein exists as a tetramer composed of a...

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Bibliografiska uppgifter
Huvudupphovsmän: Mahon, Paul J., Mirza, Anne M., Musich, Thomas A., Iorio, Ronald M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573173/
https://ncbi.nlm.nih.gov/pubmed/18753211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00581-08
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