Proteinuria and Hyperglycemia Induce Endoplasmic Reticulum Stress

The endoplasmic reticulum (ER) is an important site for protein folding and becomes “stressed” when its capacity to fold proteins is overwhelmed. In response, “unfolded protein response” (UPR) genes are induced, increasing the capacity to fold proteins; if the response is insufficient, then apoptosi...

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Главные авторы: Lindenmeyer, Maja T., Rastaldi, Maria P., Ikehata, Masami, Neusser, Matthias A., Kretzler, Matthias, Cohen, Clemens D., Schlöndorff, Detlef
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Nephrology 2008
Предметы:
Clinical Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573014/
https://ncbi.nlm.nih.gov/pubmed/18776125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007121313
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