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Proteinuria and Hyperglycemia Induce Endoplasmic Reticulum Stress

The endoplasmic reticulum (ER) is an important site for protein folding and becomes “stressed” when its capacity to fold proteins is overwhelmed. In response, “unfolded protein response” (UPR) genes are induced, increasing the capacity to fold proteins; if the response is insufficient, then apoptosi...

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Detalhes bibliográficos
Main Authors: Lindenmeyer, Maja T., Rastaldi, Maria P., Ikehata, Masami, Neusser, Matthias A., Kretzler, Matthias, Cohen, Clemens D., Schlöndorff, Detlef
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573014/
https://ncbi.nlm.nih.gov/pubmed/18776125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007121313
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