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Proteinuria and Hyperglycemia Induce Endoplasmic Reticulum Stress
The endoplasmic reticulum (ER) is an important site for protein folding and becomes “stressed” when its capacity to fold proteins is overwhelmed. In response, “unfolded protein response” (UPR) genes are induced, increasing the capacity to fold proteins; if the response is insufficient, then apoptosi...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Nephrology
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2573014/ https://ncbi.nlm.nih.gov/pubmed/18776125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007121313 |
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