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Gq-Dependent Signaling Upregulates COX2 in Glomerular Podocytes
Accumulating evidence suggests that upregulation of cyclooxygenase 2 (COX2) in glomerular podocytes promotes podocyte injury. Because Gq signaling activates calcineurin and calcineurin-dependent mechanisms are known to mediate COX2 expression, this study investigated the role of Gqα in promoting COX...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society of Nephrology
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2573009/ https://ncbi.nlm.nih.gov/pubmed/18667730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008010113 |
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