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Mms19 protein functions in nucleotide excision repair by sustaining an adequate cellular concentration of the TFIIH component Rad3

Nucleotide excision repair (NER) is a major cellular defense mechanism against DNA damage. We have investigated the role of Mms19 in NER in the yeast Saccharomyces cerevisiae. NER was deficient in the mms19 deletion mutant cell extracts, which was complemented by the NER/transcription factor TFIIH,...

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Detalhes bibliográficos
Main Authors: Kou, Haiping, Zhou, Ying, Gorospe, R. M. Charlotte, Wang, Zhigang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572961/
https://ncbi.nlm.nih.gov/pubmed/18836076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710736105
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