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Genome-wide studies highlight indirect links between human replication origins and gene regulation
To get insights into the regulation of replication initiation, we systematically mapped replication origins along 1% of the human genome in HeLa cells. We identified 283 origins, 10 times more than previously known. Origin density is strongly correlated with genomic landscapes, with clusters of clos...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2572913/ https://ncbi.nlm.nih.gov/pubmed/18838675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805208105 |
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