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PD-1-dependent mechanisms maintain peripheral tolerance of donor-reactive CD8(+) T cells to transplanted tissue
Peripheral mechanisms of self-tolerance often depend on the quiescent state of the immune system. To what degree such mechanisms can be engaged in the enhancement of allograft survival is unclear. In order to examine the role of the programmed death 1 (PD-1) pathway the maintenance of graft survival...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2572818/ https://ncbi.nlm.nih.gov/pubmed/18832687 |
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