Expression of angiotensin-converting enzyme (CD143) identifies and regulates primitive hemangioblasts derived from human pluripotent stem cells

We report that angiotensin-converting enzyme (ACE), a critical physiologic regulator of blood pressure, angiogenesis, and inflammation, is a novel marker for identifying hemangioblasts differentiating from human embryonic stem cells (hESC). We demonstrate that ACE(+)CD45(−)CD34(+/−) hemangioblasts a...

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Autori principali: Zambidis, Elias T., Soon Park, Tea, Yu, Wayne, Tam, Ada, Levine, Michal, Yuan, Xuan, Pryzhkova, Marina, Péault, Bruno
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2008
Soggetti:
Hematopoiesis and Stem Cells
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572789/
https://ncbi.nlm.nih.gov/pubmed/18728246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-03-144766
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